HORDB

ID: hor005853
Uniprot ID: Q25060
Protein name: LWamide I
Gene name: NA
Organism: Hydractinia echinata (Snail fur) (Hermit crab hydroid)
Family: LWamide neuropeptide family
Source: animal
Expression: Expressed at a low level in mature polyps and planula larvae, and at a high level in primary polyps. |In planula larvae, expressed in a narrow ring of ectodermal neurosensory cells around the widest circumference at the anterior of the larvae. In primary
Disease: NA
Comments: NA
Taxonomy: Hydractinia (genus), Hydractiniidae (family), Filifera (suborder), Anthoathecata (order), Hydroidolina (subclass), Hydrozoa (class), Cnidaria (phylum), Eumetazoa , Metazoa (kingdom), Opisthokonta , Eukaryota (superkingdom),cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: RPPGLW
Length: 6
Propeptide: MEKEMRNLMLLVLLTVILDNGIGKCNAKSEEDQDGNARNNRIDKNDDNSDSIEKYLREVTDELSKILAKRIYRDIQLRENNKKAENRQSWIGDLENLDIDSTVQRPPGLWGREADFDNTRAHDSAQISDEKQSGLWVGDAKPPGLWGRDAKPPGLWGRDAKPPGLWGRDAKPPGLWGRDAKPPGLWGRDAKPPGLWGRDAKPPGLWGRDAKPPGLWGGDAKPPGLWGRDAKPPGLWGRDAKPPGLWGRDAKPPGLWGRDAKPPGLWGRDAKPPGLWGRDTKPPGLWGRDAKPPGLWGRDAKPPSLWSKDNNVIKSRSDDAKPPGLWGRQVEDGPTKIWGDGFLDAERHIRLLKNDERFNRLEKKADMEEELRVAQGPSVTNAKDTFGELADLLRKRIVKRLHKNDSLNNRRNNKKNNKF
Signal peptide: MEKEMRNLMLLVLLTVILDNGIGKCNA
Modification: T6 Tryptophan amide
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor005853_AF2.pdb

hor005853_ESM.pdb

Mass:	81422	Formula:	C35H52N10O7
Absent amino acids:	ACDEFHIKMNQSTVY	Common amino acids:	P
pI:	10.55	Basic residues:	1
Polar residues:	1	Hydrophobic residues:	2
Hydrophobicity:	-86.67	Boman Index:	-673
Half-Life:	1 hour	Half-Life Yeast:	2 min
Half-Life E.Coli:	2 min	Aliphatic Index	65
Instability Index:	11200	Extinction Coefficient cystines:	5500
Absorbance 280nm:	1100